Let KAYAK do the searching
Based on KAYAK hotel searches, the most popular destination is Santiago (68% of total searches to Chile). The next most popular destinations are San Pedro de Atacama (18%) and Valparaíso (7%). Searches for hotels in Pucón (7%) are also popular.
Based on KAYAK hotel searches, the most popular region to stay in Chile is Region Metropolitana. Antofagasta and Valparaíso are also very popular.
KAYAK users have found double rooms in Chile for as cheap as $38 (Santiago) in the last 3 days. The average price is $231.