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Based on KAYAK hotel searches, the most popular destination is Strasbourg (50% of total searches to Alsace). The next most popular destinations are Basel (33%) and Mulhouse (8%). Searches for hotels in Saint-Louis (8%) are also popular.
KAYAK users have found double rooms in Alsace for as cheap as $67 (Mulhouse) in the last 3 days. The average price is $250.