Let KAYAK do the searching
Based on KAYAK hotel searches, the most popular destination is Strasbourg (55% of total searches to Alsace). The next most popular destinations are Basel (27%) and Mulhouse (9%). Searches for hotels in Saint-Louis (9%) are also popular.
KAYAK users have found double rooms in Alsace for as cheap as $71 (Basel) in the last 3 days. The average price is $311.