Let KAYAK do the searching
Based on KAYAK hotel searches, the most popular destination is Paris (99% of total searches to La Défense). The next most popular destinations are Courbevoie (1%) and Suresnes (0%). Searches for hotels in Neuilly-sur-Seine (0%) are also popular.
KAYAK users have found double rooms in La Défense for as cheap as $37 (Paris) in the last 3 days. The average price is $599.