Durham NC Hotel Near Duke University Medical Center With an ideal location along I-85 and the Durham Freeway and a free shuttle service to Duke University Medical Center Duke Regional Hospital and area medical facilities the Holiday Inn Express® Durham hotel offers the utmost in comfort and convenience for your next trip. We pride ourselves on being a Home Away From Home for our guests by offering great service at an affordable price. Our hotel near Duke University is just minutes from Treyburn Corporate Park and has everything you need for a productive stay in Durham NC. Use the free Wi-Fi access or our business center to keep in touch with home and the office. Our hotel is also ideal for visiting NC Central NC School of Science and Math and UNC Chapel Hill. There are a number of attractions to see on Duke University campus including the Duke Chapel Nasher Museum of Art and Sarah P Duke Gardens. In town catch a Durham Bulls game or see a show at Durham Performing Arts Center. The North Carolina Museum of Life and Science is a place where children have fun learning and our hotel near Eno River State Park is ideal for hikers and paddlers alike. You are sure to feel right at home in our comfortable accommodations. Enjoy a free hot breakfast buffet sparkling outdoor pool and free pass to work out at Millennium Fitness. Call today and let our Durham hotel exceed your expectations!